Preclinical Researcher (Bogotá)

Key Responsibilities

• Plan and execute in vitro studies to characterize mechanisms of action, efficacy, and toxicity, including but not limited to cell viability, cytotoxicity, proliferation, apoptosis, and target engagement.
• Culture and maintain mammalian cell lines (adherent and suspension, primary cells are a plus) using aseptic technique and establish 2D and 3D models as needed.
• Perform biochemical and molecular biology assays (ELISA, qPCR/RT-qPCR, Western blot, flow cytometry, gel electrophoresis, immunofluorescence).
• Design and execute peptide studies, including handling, solubility and stability assessments, and activity assays.
• Analyze and interpret data with rigorous statistics (IC₅₀/EC₅₀ curve fitting, t-tests, ANOVA, and appropriate multiple-comparison controls) and generate precise figures and technical reports to inform project decisions.
• Collaborate cross-functionally to transfer assays, support formulation c...